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Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration
The nuclear import receptors importin β and transportin play a different role in mitosis: both act phenotypically as spatial regulators to ensure that mitotic spindle, nuclear membrane, and nuclear pore assembly occur exclusively around chromatin. Importin β is known to act by repressing assembly fa...
Autores principales: | Bernis, Cyril, Swift-Taylor, Beth, Nord, Matthew, Carmona, Sarah, Chook, Yuh Min, Forbes, Douglass J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967982/ https://www.ncbi.nlm.nih.gov/pubmed/24478460 http://dx.doi.org/10.1091/mbc.E13-08-0506 |
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