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Parent-of-Origin Effects Implicate Epigenetic Regulation of Experimental Autoimmune Encephalomyelitis and Identify Imprinted Dlk1 as a Novel Risk Gene
Parent-of-origin effects comprise a range of genetic and epigenetic mechanisms of inheritance. Recently, detection of such effects implicated epigenetic mechanisms in the etiology of multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system. We here sought to dissect the...
Autores principales: | Stridh, Pernilla, Ruhrmann, Sabrina, Bergman, Petra, Thessén Hedreul, Mélanie, Flytzani, Sevasti, Beyeen, Amennai Daniel, Gillett, Alan, Krivosija, Nina, Öckinger, Johan, Ferguson-Smith, Anne C., Jagodic, Maja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967983/ https://www.ncbi.nlm.nih.gov/pubmed/24676147 http://dx.doi.org/10.1371/journal.pgen.1004265 |
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