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Mechanism of μ-Conotoxin PIIIA Binding to the Voltage-Gated Na(+) Channel Na(V)1.4

Several subtypes of voltage-gated Na(+) (Na(V)) channels are important targets for pain management. μ-Conotoxins isolated from venoms of cone snails are potent and specific blockers of different Na(V) channel isoforms. The inhibitory effect of μ-conotoxins on Na(V) channels has been examined extensi...

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Detalles Bibliográficos
Autores principales:	Chen, Rong, Robinson, Anna, Chung, Shin-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968119/ https://www.ncbi.nlm.nih.gov/pubmed/24676211 http://dx.doi.org/10.1371/journal.pone.0093267

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