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Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic Molecules against West Nile Virus

Previously, our group engineered a plant-derived monoclonal antibody (MAb) (pHu-E16) that efficiently treated West Nile virus (WNV) infection in mice. In this study, we developed several pHu-E16 variants to improve its efficacy. These variants included a single-chain variable fragment (scFv) of pHu-...

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Detalles Bibliográficos
Autores principales:	He, Junyun, Lai, Huafang, Engle, Michael, Gorlatov, Sergey, Gruber, Clemens, Steinkellner, Herta, Diamond, Michael S., Chen, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968140/ https://www.ncbi.nlm.nih.gov/pubmed/24675995 http://dx.doi.org/10.1371/journal.pone.0093541

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