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Rare Variants Detection with Kernel Machine Learning Based on Likelihood Ratio Test
This paper mainly utilizes likelihood-based tests to detect rare variants associated with a continuous phenotype under the framework of kernel machine learning. Both the likelihood ratio test (LRT) and the restricted likelihood ratio test (ReLRT) are investigated. The relationship between the kernel...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968153/ https://www.ncbi.nlm.nih.gov/pubmed/24675868 http://dx.doi.org/10.1371/journal.pone.0093355 |