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Insulin Sensitivity and Insulin Clearance are Heritable and Have Strong Genetic Correlation in Mexican Americans

OBJECTIVE: We describe the GUARDIAN (Genetics UndeRlying DIAbetes in HispaNics) consortium, along with heritability estimates and genetic and environmental correlations of insulin sensitivity and metabolic clearance rate of insulin (MCRI). DESIGN AND METHODS: GUARDIAN is comprised of seven cohorts,...

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Detalles Bibliográficos
Autores principales:	Goodarzi, Mark O., Langefeld, Carl D., Xiang, Anny H., Chen, Yii-Der I., Guo, Xiuqing, Hanley, Anthony J. G., Raffel, Leslie J., Kandeel, Fouad, Buchanan, Thomas A., Norris, Jill M., Fingerlin, Tasha E., Lorenzo, Carlos, Rewers, Marian J., Haffner, Steven M., Bowden, Donald W., Rich, Stephen S., Bergman, Richard N., Rotter, Jerome I., Watanabe, Richard M., Wagenknecht, Lynne E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968231/ https://www.ncbi.nlm.nih.gov/pubmed/24124113 http://dx.doi.org/10.1002/oby.20639

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