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Fetal development of the minor lung segment

The mediobasal segment (S7) of the right lung has been considered to correspond to the cardiac lobe generally seen in mammals. To investigate fetal development of the right mediobasal segmental bronchus (B7), we examined paraffin-embedded serial sections of 15 embrynic and fetal lungs at 7-8 weeks (...

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Autores principales: Abe, Shinichi, Yamamoto, Masahito, Noguchi, Taku, Yoshimoto, Toshihito, Kinoshita, Hideaki, Matsunaga, Satoru, Murakami, Gen, Rodríguez-Vázquez, Jose Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968262/
https://www.ncbi.nlm.nih.gov/pubmed/24693478
http://dx.doi.org/10.5115/acb.2014.47.1.12
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author Abe, Shinichi
Yamamoto, Masahito
Noguchi, Taku
Yoshimoto, Toshihito
Kinoshita, Hideaki
Matsunaga, Satoru
Murakami, Gen
Rodríguez-Vázquez, Jose Francisco
author_facet Abe, Shinichi
Yamamoto, Masahito
Noguchi, Taku
Yoshimoto, Toshihito
Kinoshita, Hideaki
Matsunaga, Satoru
Murakami, Gen
Rodríguez-Vázquez, Jose Francisco
author_sort Abe, Shinichi
collection PubMed
description The mediobasal segment (S7) of the right lung has been considered to correspond to the cardiac lobe generally seen in mammals. To investigate fetal development of the right mediobasal segmental bronchus (B7), we examined paraffin-embedded serial sections of 15 embrynic and fetal lungs at 7-8 weeks (serial sections) as well as semiserial sections of 8 fetuses at 15-18 weeks (semiserial sections). All of the smaller specimens did not contain B7, but 2 of the 8 larger specimens carried B7: one was found in the immediately anterior side of the inferior pulmonary vein, while in the other, the subdivisions (B7a, B7b) were overriding the vein. Although the incidence might be underestimated because of observations using semiserial sections, the B7 was most likely to develop secondarily during a period from 8 to 15 weeks. Fetal topographical changes (mainly, the descent) of the middle lobe and the inferior pulmonary vein might relate with the secondarily budding of B7. The present result does not reduce a clinical relevance of B7 as a segmental bronchus of the lung segment system.
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spelling pubmed-39682622014-04-01 Fetal development of the minor lung segment Abe, Shinichi Yamamoto, Masahito Noguchi, Taku Yoshimoto, Toshihito Kinoshita, Hideaki Matsunaga, Satoru Murakami, Gen Rodríguez-Vázquez, Jose Francisco Anat Cell Biol Original Article The mediobasal segment (S7) of the right lung has been considered to correspond to the cardiac lobe generally seen in mammals. To investigate fetal development of the right mediobasal segmental bronchus (B7), we examined paraffin-embedded serial sections of 15 embrynic and fetal lungs at 7-8 weeks (serial sections) as well as semiserial sections of 8 fetuses at 15-18 weeks (semiserial sections). All of the smaller specimens did not contain B7, but 2 of the 8 larger specimens carried B7: one was found in the immediately anterior side of the inferior pulmonary vein, while in the other, the subdivisions (B7a, B7b) were overriding the vein. Although the incidence might be underestimated because of observations using semiserial sections, the B7 was most likely to develop secondarily during a period from 8 to 15 weeks. Fetal topographical changes (mainly, the descent) of the middle lobe and the inferior pulmonary vein might relate with the secondarily budding of B7. The present result does not reduce a clinical relevance of B7 as a segmental bronchus of the lung segment system. Korean Association of Anatomists 2014-03 2014-03-13 /pmc/articles/PMC3968262/ /pubmed/24693478 http://dx.doi.org/10.5115/acb.2014.47.1.12 Text en Copyright © 2014. Anatomy & Cell Biology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Abe, Shinichi
Yamamoto, Masahito
Noguchi, Taku
Yoshimoto, Toshihito
Kinoshita, Hideaki
Matsunaga, Satoru
Murakami, Gen
Rodríguez-Vázquez, Jose Francisco
Fetal development of the minor lung segment
title Fetal development of the minor lung segment
title_full Fetal development of the minor lung segment
title_fullStr Fetal development of the minor lung segment
title_full_unstemmed Fetal development of the minor lung segment
title_short Fetal development of the minor lung segment
title_sort fetal development of the minor lung segment
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968262/
https://www.ncbi.nlm.nih.gov/pubmed/24693478
http://dx.doi.org/10.5115/acb.2014.47.1.12
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