Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals

Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of...

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Autores principales: Remsberg, Connie M., Good, Renee L., Davies, Neal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968348/
https://www.ncbi.nlm.nih.gov/pubmed/27721342
http://dx.doi.org/10.3390/pharmaceutics2010050
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author Remsberg, Connie M.
Good, Renee L.
Davies, Neal M.
author_facet Remsberg, Connie M.
Good, Renee L.
Davies, Neal M.
author_sort Remsberg, Connie M.
collection PubMed
description Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of vitamin E succinate varied from 0-130% of the stated label content with two products containing vitamin E acetate rather than vitamin E succinate. Expected polyphenols were found in 7 of the 8 supplement products. None of the polyphenol supplements contained content within 100-120% of label claims. The present study indicates a lack of uniformity in nutraceutical products.
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spelling pubmed-39683482014-03-28 Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals Remsberg, Connie M. Good, Renee L. Davies, Neal M. Pharmaceutics Article Label claims of vitamin E succinate and polyphenolic nutraceuticals are assessed. A validated HPLC method was utilized to assess vitamin E succinate products. Three novel LC/MS methods were used to assess the polyphenols, pterostilbene, phloretin, and myricetin, in dietary supplements. The amount of vitamin E succinate varied from 0-130% of the stated label content with two products containing vitamin E acetate rather than vitamin E succinate. Expected polyphenols were found in 7 of the 8 supplement products. None of the polyphenol supplements contained content within 100-120% of label claims. The present study indicates a lack of uniformity in nutraceutical products. Molecular Diversity Preservation International 2010-03-08 /pmc/articles/PMC3968348/ /pubmed/27721342 http://dx.doi.org/10.3390/pharmaceutics2010050 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an Open Access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Remsberg, Connie M.
Good, Renee L.
Davies, Neal M.
Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title_full Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title_fullStr Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title_full_unstemmed Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title_short Ingredient Consistency of Commercially Available Polyphenol and Tocopherol Nutraceuticals
title_sort ingredient consistency of commercially available polyphenol and tocopherol nutraceuticals
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968348/
https://www.ncbi.nlm.nih.gov/pubmed/27721342
http://dx.doi.org/10.3390/pharmaceutics2010050
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AT daviesnealm ingredientconsistencyofcommerciallyavailablepolyphenolandtocopherolnutraceuticals

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