Immune Checkpoint Blockade in Cancer Treatment: A Double-Edged Sword Cross-Targeting the Host as an “Innocent Bystander”

Targeted immune checkpoint blockade augments anti-tumor immunity and induces durable responses in patients with melanoma and other solid tumors. It also induces specific “immune-related adverse events” (irAEs). IrAEs mainly include gastrointestinal, dermatological, hepatic and endocrinological toxic...

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Detalles Bibliográficos
Autores principales: Gelao, Lucia, Criscitiello, Carmen, Esposito, Angela, Goldhirsch, Aron, Curigliano, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968368/
https://www.ncbi.nlm.nih.gov/pubmed/24594636
http://dx.doi.org/10.3390/toxins6030914

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