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Constitutive Somatostatin Receptor Subtype-3 Signaling Suppresses Growth Hormone Synthesis

Somatostatin signals through somatostatin receptor subtypes (SSTR) 2 and 5 to attenuate GH secretion. Although expressed in normal pituitary glands and in GH-secreting pituitary tumors, SSTR3 function was unclear, and we have now determined the role of SSTR3 in somatotroph function. Stable rat pitui...

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Detalles Bibliográficos
Autores principales:	Eigler, Tamar, Ben-Shlomo, Anat, Zhou, Cuiqi, Khalafi, Ramtin, Ren, Song-Guang, Melmed, Shlomo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968402/ https://www.ncbi.nlm.nih.gov/pubmed/24606125 http://dx.doi.org/10.1210/me.2013-1327

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