Cargando…

Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

Tau is a major microtubule-associated protein in brain neurons. Its misfolding and accumulation cause neurodegenerative diseases characterized by brain atrophy and dementia, named tauopathies. Genetic forms are caused by mutations of microtubule-associated protein tau gene (MAPT). Tau is expressed a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rossi, Giacomina, Conconi, Donatella, Panzeri, Elena, Paoletta, Laura, Piccoli, Elena, Ferretti, Maria Giulia, Mangieri, Michela, Ruggerone, Margherita, Dalprà, Leda, Tagliavini, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968519/ https://www.ncbi.nlm.nih.gov/pubmed/24218087 http://dx.doi.org/10.1007/s10048-013-0380-y

Ejemplares similares

Chromosomal imbalances in human bladder urothelial carcinoma: similarities and differences between biopsy samples and cancer stem-like cells
por: Conconi, Donatella, et al.
Publicado: (2014)

DNA copy number alterations and PPARG amplification in a patient with multifocal bladder urothelial carcinoma
por: Conconi, Donatella, et al.
Publicado: (2012)

Familial globular glial tauopathy linked to MAPT mutations: molecular neuropathology and seeding capacity of a prototypical mixed neuronal and glial tauopathy
por: Ferrer, Isidro, et al.
Publicado: (2020)

Using Copy Number Alterations to Identify New Therapeutic Targets for Bladder Carcinoma
por: Conconi, Donatella, et al.
Publicado: (2016)

Chromosomal Aberrations in Bladder Cancer: Fresh versus Formalin Fixed Paraffin Embedded Tissue and Targeted FISH versus Wide Microarray-Based CGH Analysis
por: Panzeri, Elena, et al.
Publicado: (2011)

MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
por: Trabzuni, Daniah, et al.
Publicado: (2012)

Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies
por: Forrest, Shelley L, et al.
Publicado: (2018)

Cytogenetics of Premature Ovarian Failure: An Investigation on 269 Affected Women
por: Baronchelli, Simona, et al.
Publicado: (2011)

Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies
por: Easton, Amy, et al.
Publicado: (2022)

Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations
por: Caneus, Julbert, et al.
Publicado: (2018)

Investigating the role of X chromosome breakpoints in premature ovarian failure
por: Baronchelli, Simona, et al.
Publicado: (2012)

The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
por: Kara, Eleanna, et al.
Publicado: (2012)

Stimulation of synaptic activity promotes TFEB-mediated clearance of pathological MAPT/Tau in cellular and mouse models of tauopathies
por: Akwa, Yvette, et al.
Publicado: (2022)

Familiar unbalanced complex rearrangements involving 13 p-arm: description of two cases
por: Conconi, Donatella, et al.
Publicado: (2018)

Analysis of copy number alterations in bladder cancer stem cells revealed a prognostic role of LRP1B
por: Conconi, Donatella, et al.
Publicado: (2022)

Active Interpersonal Touch Gives Rise to the Social Softness Illusion
por: Gentsch, Antje, et al.
Publicado: (2015)

Developmental Expression of 4-Repeat-Tau Induces Neuronal Aneuploidy in Drosophila Tauopathy Models
por: Malmanche, Nicolas, et al.
Publicado: (2017)

Refining the Phenotype of Recurrent Rearrangements of Chromosome 16
por: Redaelli, Serena, et al.
Publicado: (2019)

Potential role of BCL2 in the recurrence of uterine smooth muscle tumors of uncertain malignant potential
por: Conconi, Donatella, et al.
Publicado: (2017)

Characterization of Chromosomal Breakpoints in 12 Cases with 8p Rearrangements Defines a Continuum of Fragility of the Region
por: Redaelli, Serena, et al.
Publicado: (2022)

Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathy
por: Wobst, Heike J., et al.
Publicado: (2017)

iPS Cell-Based Model for MAPT Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression
por: Strauß, Tabea, et al.
Publicado: (2021)

Dropsy, and the Pathological Conditions That Give Rise to It
por: Davis, N. S.
Publicado: (1863)

14q32.3-qter trisomic segment: a case report and literature review
por: Villa, Nicoletta, et al.
Publicado: (2016)

Genomic Complexity and Complex Chromosomal Rearrangements in Genetic Diagnosis: Two Illustrative Cases on Chromosome 7
por: Villa, Nicoletta, et al.
Publicado: (2023)

Genomic and Epigenomic Profile of Uterine Smooth Muscle Tumors of Uncertain Malignant Potential (STUMPs) Revealed Similarities and Differences with Leiomyomas and Leiomyosarcomas
por: Conconi, Donatella, et al.
Publicado: (2021)

Sex chromosome aneuploidies give rise to changes in the circular RNA profile: A circular transcriptome-wide study of Turner and Klinefelter syndrome across different tissues
por: Johannsen, Emma B., et al.
Publicado: (2022)

Entropy gives rise to topologically associating domains
por: Vasquez, Paula A., et al.
Publicado: (2016)

Entropic singularities give rise to quantum transmission
por: Siddhu, Vikesh
Publicado: (2021)

Different MAPT haplotypes influence expression of total MAPT in postmortem brain tissue
por: Tauber, Christina V., et al.
Publicado: (2023)

The Effect of Culture on Human Bone Marrow Mesenchymal Stem Cells: Focus on DNA Methylation Profiles
por: Bentivegna, Angela, et al.
Publicado: (2016)

In vitro anticancer drug test: A new method emerges from the model of glioma stem cells
por: Riva, Gabriele, et al.
Publicado: (2014)

Conjugation of Aminoadamantane and γ-Carboline Pharmacophores Gives Rise to Unexpected Properties of Multifunctional Ligands
por: Bachurin, Sergey O., et al.
Publicado: (2021)

H1-MAPT and the Risk for Familial Essential Tremor
por: García-Martín, Elena, et al.
Publicado: (2012)

Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels
por: Allen, Mariet, et al.
Publicado: (2014)

Unexpected frequency of genomic alterations in histologically normal colonic tissue from colon cancer patients
por: Conconi, Donatella, et al.
Publicado: (2016)

A unique lineage gives rise to the meibomian gland
por: Call, Mindy, et al.
Publicado: (2016)

Swarm dynamics may give rise to Lévy flights
por: Reynolds, Andrew M., et al.
Publicado: (2016)

Monocyte progenitors give rise to multinucleated giant cells
por: Lösslein, Anne Kathrin, et al.
Publicado: (2021)

How Proprioception Gives Rise to Self-Others-Knowledge
por: Pacholik-Żuromska, Anita
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fuv02v1gko58gljr081h5gj8rh