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Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis

We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuri...

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Autores principales: Venkatesan, E. P., Pranesh, M. B., Gnanashanmugam, G., Balasubramaniam, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968597/
https://www.ncbi.nlm.nih.gov/pubmed/24701043
http://dx.doi.org/10.4103/0971-4065.127898
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author Venkatesan, E. P.
Pranesh, M. B.
Gnanashanmugam, G.
Balasubramaniam, J.
author_facet Venkatesan, E. P.
Pranesh, M. B.
Gnanashanmugam, G.
Balasubramaniam, J.
author_sort Venkatesan, E. P.
collection PubMed
description We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India.
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spelling pubmed-39685972014-04-03 Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis Venkatesan, E. P. Pranesh, M. B. Gnanashanmugam, G. Balasubramaniam, J. Indian J Nephrol Case Report We report a 55-year-old female who presented to the emergency department with acute onset quadriparesis. She was diagnosed to have acquired immunodeficiency syndrome 7 years ago and was on tenofovir based anti-retroviral therapy for past 10 months. As the patient also had hypophosphatemia, glucosuria and proteinuria Fanconi syndrome (FS) was suspected. She improved dramatically over next 12 h to regain normal power and also her renal functions improved over next few days. Tenofovir induced FS presenting as hypokalemic paralysis is very rare complication and is the first case reported from India. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3968597/ /pubmed/24701043 http://dx.doi.org/10.4103/0971-4065.127898 Text en Copyright: © Indian Journal of Nephrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Venkatesan, E. P.
Pranesh, M. B.
Gnanashanmugam, G.
Balasubramaniam, J.
Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title_full Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title_fullStr Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title_full_unstemmed Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title_short Tenofovir induced Fanconi syndrome: A rare cause of hypokalemic paralysis
title_sort tenofovir induced fanconi syndrome: a rare cause of hypokalemic paralysis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968597/
https://www.ncbi.nlm.nih.gov/pubmed/24701043
http://dx.doi.org/10.4103/0971-4065.127898
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