Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

To achieve its precise neural connectivity, the developing mammalian nervous system undergoes extensive activity-dependent synapse remodeling. Recently microglial cells have been shown to be responsible for a portion of synaptic remodeling, but the remaining mechanisms remain mysterious. Here we rep...

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Detalles Bibliográficos
Autores principales: Chung, Won-Suk, Clarke, Laura E., Wang, Gordon X., Stafford, Benjamin K., Sher, Alexander, Chakraborty, Chandrani, Joung, Julia, Foo, Lynette C., Thompson, Andrew, Chen, Chinfei, Smith, Stephen J., Barres, Ben A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969024/
https://www.ncbi.nlm.nih.gov/pubmed/24270812
http://dx.doi.org/10.1038/nature12776

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