Cargando…

The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation

TA (toxin–antitoxin) systems are widely distributed amongst bacteria and are associated with the formation of antibiotic tolerant (persister) cells that may have involvement in chronic and recurrent disease. We show that overexpression of the Burkholderia pseudomallei HicA toxin causes growth arrest...

Descripción completa

Detalles Bibliográficos
Autores principales: Butt, Aaron, Higman, Victoria A., Williams, Christopher, Crump, Matthew P., Hemsley, Claudia M., Harmer, Nicholas, Titball, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969222/
https://www.ncbi.nlm.nih.gov/pubmed/24502667
http://dx.doi.org/10.1042/BJ20140073