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Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin()
Mammalian toll-like receptor 5 (TLR5) senses flagellin of several bacterial species and has been described to activate the innate immune system. To assess the role of bovine TLR5 (boTLR5) in the cattle system, we cloned and successfully expressed boTLR5 in human embryonic kidney (HEK) 293 cells, as...
Autores principales: | Metcalfe, Hannah J., La Ragione, Roberto M., Smith, David G.E., Werling, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969226/ https://www.ncbi.nlm.nih.gov/pubmed/24461722 http://dx.doi.org/10.1016/j.vetimm.2013.12.006 |
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