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Functional characterisation of bovine TLR5 indicates species-specific recognition of flagellin()

Mammalian toll-like receptor 5 (TLR5) senses flagellin of several bacterial species and has been described to activate the innate immune system. To assess the role of bovine TLR5 (boTLR5) in the cattle system, we cloned and successfully expressed boTLR5 in human embryonic kidney (HEK) 293 cells, as...

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Detalles Bibliográficos
Autores principales: Metcalfe, Hannah J., La Ragione, Roberto M., Smith, David G.E., Werling, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969226/
https://www.ncbi.nlm.nih.gov/pubmed/24461722
http://dx.doi.org/10.1016/j.vetimm.2013.12.006

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