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Recombinant antigens based on toxins A and B of Clostridium difficile that evoke a potent toxin-neutralising immune response()
Infection with the bacterium Clostridium difficile causes symptoms ranging from mild to severe diarrhoea with life-threatening complications and remains a significant burden to healthcare systems throughout the developed world. Two potent cytotoxins, TcdA and TcdB are the prime mediators of the synd...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969267/ https://www.ncbi.nlm.nih.gov/pubmed/24342251 http://dx.doi.org/10.1016/j.vaccine.2013.11.099 |