Recombinant antigens based on toxins A and B of Clostridium difficile that evoke a potent toxin-neutralising immune response()

Infection with the bacterium Clostridium difficile causes symptoms ranging from mild to severe diarrhoea with life-threatening complications and remains a significant burden to healthcare systems throughout the developed world. Two potent cytotoxins, TcdA and TcdB are the prime mediators of the synd...

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Detalles Bibliográficos
Autores principales: Maynard-Smith, Michael, Ahern, Helen, McGlashan, Joanna, Nugent, Philip, Ling, Roger, Denton, Harriet, Coxon, Ruth, Landon, John, Roberts, April, Shone, Clifford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969267/
https://www.ncbi.nlm.nih.gov/pubmed/24342251
http://dx.doi.org/10.1016/j.vaccine.2013.11.099

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