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Pain without Nociceptors? Nav1.7-Independent Pain Mechanisms

Nav1.7, a peripheral neuron voltage-gated sodium channel, is essential for pain and olfaction in mice and humans. We examined the role of Nav1.7 as well as Nav1.3, Nav1.8, and Nav1.9 in different mouse models of chronic pain. Constriction-injury-dependent neuropathic pain is abolished when Nav1.7 is...

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Detalles Bibliográficos
Autores principales:	Minett, Michael S., Falk, Sarah, Santana-Varela, Sonia, Bogdanov, Yury D., Nassar, Mohammed A., Heegaard, Anne-Marie, Wood, John N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969273/ https://www.ncbi.nlm.nih.gov/pubmed/24440715 http://dx.doi.org/10.1016/j.celrep.2013.12.033

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