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Cell-Nonautonomous Effects of dFOXO/DAF-16 in Aging

Drosophila melanogaster and Caenorhabditis elegans each carry a single representative of the Forkhead box O (FoxO) family of transcription factors, dFOXO and DAF-16, respectively. Both are required for lifespan extension by reduced insulin/Igf signaling, and their activation in key tissues can exten...

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Detalles Bibliográficos
Autores principales:	Alic, Nazif, Tullet, Jennifer M., Niccoli, Teresa, Broughton, Susan, Hoddinott, Matthew P., Slack, Cathy, Gems, David, Partridge, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969275/ https://www.ncbi.nlm.nih.gov/pubmed/24508462 http://dx.doi.org/10.1016/j.celrep.2014.01.015

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