Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging

Aging is associated with a progressive decline in immune function (immunosenescence) resulting in an increased susceptibility to viral and bacterial infections. Here we show reduced expression of Toll-like receptor 1 (TLR1) in polymorphonuclear leukocytes (PMN) and an underlying age-dependent defici...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Feng, Guo, Xiuyang, Wang, Xiaomei, Yuan, Xiaoling, Chen, Shu, Malawista, Stephen E., Bockenstedt, Linda K., Allore, Heather G., Montgomery, Ruth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969281/
https://www.ncbi.nlm.nih.gov/pubmed/24595889

Ejemplares similares

Ejemplares similares