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Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions()

The transfer of a laboratory process into a manufacturing facility is one of the most critical steps required for the large scale production of cell-based therapy products. This study describes the first published protocol for scalable automated expansion of human induced pluripotent stem cell lines...

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Detalles Bibliográficos
Autores principales: Soares, Filipa A.C., Chandra, Amit, Thomas, Robert J., Pedersen, Roger A., Vallier, Ludovic, Williams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969287/
https://www.ncbi.nlm.nih.gov/pubmed/24440272
http://dx.doi.org/10.1016/j.jbiotec.2013.12.009