Bacterial expression of human kynurenine 3-monooxygenase: Solubility, activity, purification()

Kynurenine 3-monooxygenase (KMO) is an enzyme central to the kynurenine pathway of tryptophan metabolism. KMO has been implicated as a therapeutic target in several disease states, including Huntington’s disease. Recombinant human KMO protein production is challenging due to the presence of transmem...

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Detalles Bibliográficos
Autores principales: Wilson, K., Mole, D.J., Binnie, M., Homer, N.Z.M., Zheng, X., Yard, B.A., Iredale, J.P., Auer, M., Webster, S.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969302/
https://www.ncbi.nlm.nih.gov/pubmed/24316190
http://dx.doi.org/10.1016/j.pep.2013.11.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969302/
https://www.ncbi.nlm.nih.gov/pubmed/24316190
http://dx.doi.org/10.1016/j.pep.2013.11.015

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