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Activation and Characterization of a Cryptic Polycyclic Tetramate Macrolactam Biosynthetic Gene Cluster

Polycyclic tetramate macrolactams (PTMs) are a widely distributed class of natural products with important biological activities. However, many of them have not been characterized. Here we apply a plug and play synthetic biology strategy to activate a cryptic PTM biosynthetic gene cluster SGR810-815...

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Detalles Bibliográficos
Autores principales:	Luo, Yunzi, Huang, Hua, Liang, Jing, Wang, Meng, Lu, Lu, Shao, Zengyi, Cobb, Ryan E., Zhao, Huimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969335/ https://www.ncbi.nlm.nih.gov/pubmed/24305602 http://dx.doi.org/10.1038/ncomms3894

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