Cargando…

Interferon-γ Induces Senescence in Normal Human Melanocytes

BACKGROUND: Interferon-γ (IFN-γ) plays an important role in the proceedings of vitiligo through recruiting lymphocytes to the lesional skin. However, the potential effects of IFN-γ on skin melanocytes and the subsequent contribution to the vitiligo pathogenesis are still unclear. OBJECTIVE: To inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Suiquan, Zhou, Miaoni, Lin, Fuquan, Liu, Dongyin, Hong, Weisong, Lu, Liangjun, Zhu, Yiping, Xu, Aie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969336/ https://www.ncbi.nlm.nih.gov/pubmed/24681574 http://dx.doi.org/10.1371/journal.pone.0093232

Ejemplares similares

The role of VIT1/FBXO11 in the regulation of apoptosis and tyrosinase export from endoplasmic reticulum in cultured melanocytes
por: Guan, Cuiping, et al.
Publicado: (2022)

Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytes
por: LIN, FUQUAN, et al.
Publicado: (2012)

Inhibition of Fam114A1 protects melanocytes from apoptosis through higher RACK1 expression
por: Zhou, Miaoni, et al.
Publicado: (2021)

CD8(+) T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis
por: WU, JILONG, et al.
Publicado: (2013)

Pathogenic Th2 Cytokine Profile Skewing by IFN-γ-Responding Vitiligo Fibroblasts via CCL2/CCL8
por: Jin, Rong, et al.
Publicado: (2023)

CXCL9 as a key biomarker of vitiligo activity and prediction of the success of cultured melanocyte transplantation
por: Lin, Fuquan, et al.
Publicado: (2021)

Novel approaches to vitiligo treatment via modulation of mTOR and NF-κB pathways in human skin melanocytes
por: Wan, Jerry, et al.
Publicado: (2017)

Interferon-γ links UV to melanocyte activation and promotes melanomagenesis
por: Zaidi, M. Raza, et al.
Publicado: (2011)

Amphiregulin Regulates Melanocytic Senescence
por: Pommer, Michaela, et al.
Publicado: (2021)

RIPK1 regulates the survival of human melanocytes upon endoplasmic reticulum stress
por: Sun, Xuecheng, et al.
Publicado: (2020)

Antibodies to normal human melanocytes in vitiligo
Publicado: (1983)

PP2A-B56α Controls Oncogene-Induced Senescence in Normal and Tumor Human Melanocytic Cells
por: Mannava, Sudha, et al.
Publicado: (2011)

Signalling by senescent melanocytes hyperactivates hair growth
por: Wang, Xiaojie, et al.
Publicado: (2023)

Current Understanding of the Role of Senescent Melanocytes in Skin Ageing
por: Hughes, Bethany K., et al.
Publicado: (2022)

Detection of Cellular Senescence in Human Primary Melanocytes and Malignant Melanoma Cells In Vitro
por: Zimmermann, Tom, et al.
Publicado: (2022)

Two Cases of Focal Scrotal Vitiligo Successfully Treated by Autologous Cultured Melanocyte Transplantation
por: Li, Xiaowen, et al.
Publicado: (2014)

MicroRNA-421 participates in vitiligo development through regulating human melanocyte survival by targeting receptor-interacting serine/threonine kinase 1
por: Sun, Xuecheng, et al.
Publicado: (2020)

PAX3 Expression in Normal Skin Melanocytes and Melanocytic Lesions (Naevi and Melanomas)
por: Medic, Sandra, et al.
Publicado: (2010)

Targeting senescent dermal fibroblasts responsible for hyperactive melanocytes in melasma
por: Wan, Jing, et al.
Publicado: (2023)

The host transcriptome change involved in the inhibitory effect of exogenous interferon-γ on Getah virus replication
por: Li, Jialei, et al.
Publicado: (2023)

Surface antigens of melanoma and melanocytes. Specificity of induction of Ia antigens by human gamma-interferon
Publicado: (1984)

Dynamic assembly of chromatin complexes during cellular senescence: implications for the growth arrest of human melanocytic nevi
por: Bandyopadhyay, Debdutta, et al.
Publicado: (2007)

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
por: Liebig, Janika K., et al.
Publicado: (2020)

Common Delayed Senescence of Melanocytes from Multiple Primary Melanoma Patients
por: Kohli, Jaskaren S., et al.
Publicado: (2017)

Senescent melanocytes driven by glycolytic changes are characterized by melanosome transport dysfunction
por: Park, Young Joon, et al.
Publicado: (2023)

Epitope Mapping of Neutralizing Monoclonal Antibodies to Human Interferon-γ Using Human-Bovine Interferon-γ Chimeras
por: Zuber, Bartek, et al.
Publicado: (2016)

A Micro-RNA Connection in BRaf (V600E)-Mediated Premature Senescence of Human Melanocytes
por: Ren, Gang, et al.
Publicado: (2012)

EPR spectroscopy of chlorpromazine-induced free radical formation in normal human melanocytes
por: Otręba, Michał, et al.
Publicado: (2015)

In vitro melanogenesis inhibition by fluphenazine and prochlorperazine in normal human melanocytes lightly pigmented
por: Otręba, Michał, et al.
Publicado: (2018)

In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells
por: Leikam, C, et al.
Publicado: (2015)

A new model to investigate UVB-induced cellular senescence and pigmentation in melanocytes
por: Martic, Ines, et al.
Publicado: (2020)

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression
por: Kohli, Jaskaren, et al.
Publicado: (2022)

Characterization of Primary Cultures of Normal and Neoplastic Canine Melanocytes
por: Sforna, Monica, et al.
Publicado: (2021)

A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte
por: An, Jianhong, et al.
Publicado: (2011)

Human cytomegalovirus UL23 inhibits transcription of interferon-γ stimulated genes and blocks antiviral interferon-γ responses by interacting with human N-myc interactor protein
por: Feng, Linyuan, et al.
Publicado: (2018)

Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes
por: Lim, Hee-Sun, et al.
Publicado: (2016)

Effect of norfloxacin and moxifloxacin on melanin synthesis and antioxidant enzymes activity in normal human melanocytes
por: Beberok, Artur, et al.
Publicado: (2014)

Expression of interferon-γ in human adrenal gland and kidney tumours
por: Li, Q, et al.
Publicado: (2007)

Dermal Mesenchymal Stem Cells (DMSCs) Inhibit Skin-Homing CD8+ T Cell Activity, a Determining Factor of Vitiligo Patients’ Autologous Melanocytes Transplantation Efficiency
por: Zhou, Miao-ni, et al.
Publicado: (2013)

The relative contributions of the p53 and pRb pathways in oncogene-induced melanocyte senescence
por: Haferkamp, Sebastian, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_u3skkd80mjisa8rlgcsg6737s8