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Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide
Epidermal growth factor receptor (EGFR) is a crucial protein that plays an important role in the maintenance and development of glioblastomas. The silencing or knockdown of EGFR is possible by administering a small interfering ribonucleic acid (siRNA). Lipid nanocapsules (LNCs) covered by chitosan w...
Autores principales: | Messaoudi, Khaled, Saulnier, Patrick, Boesen, Kim, Benoit, Jean-Pierre, Lagarce, Frederic |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969342/ https://www.ncbi.nlm.nih.gov/pubmed/24711698 http://dx.doi.org/10.2147/IJN.S59134 |
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