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Evaluation of a Human BCG Challenge Model to Assess Antimycobacterial Immunity Induced by BCG and a Candidate Tuberculosis Vaccine, MVA85A, Alone and in Combination

Background. A new vaccine is urgently needed to combat tuberculosis. However, without a correlate of protection, selection of the vaccines to take forward into large-scale efficacy trials is difficult. Use of bacille Calmette-Guérin (BCG) as a surrogate for human Mycobacterium tuberculosis challenge...

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Detalles Bibliográficos
Autores principales:	Harris, Stephanie A., Meyer, Joel, Satti, Iman, Marsay, Leanne, Poulton, Ian D., Tanner, Rachel, Minassian, Angela M., Fletcher, Helen A., McShane, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969545/ https://www.ncbi.nlm.nih.gov/pubmed/24273174 http://dx.doi.org/10.1093/infdis/jit647

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