Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome

Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides. Among antico...

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Autores principales: Shingade, Pravin U, Wankhede, Vaishali, Kataria, Pritam S, Sonone, Nitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
E-Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969702/
https://www.ncbi.nlm.nih.gov/pubmed/24700960
http://dx.doi.org/10.4103/0019-5154.127715
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author Shingade, Pravin U
Wankhede, Vaishali
Kataria, Pritam S
Sonone, Nitin
author_facet Shingade, Pravin U
Wankhede, Vaishali
Kataria, Pritam S
Sonone, Nitin
author_sort Shingade, Pravin U
collection PubMed
description Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides. Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin.
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spelling pubmed-39697022014-04-03 Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome Shingade, Pravin U Wankhede, Vaishali Kataria, Pritam S Sonone, Nitin Indian J Dermatol E-Case Report Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides. Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3969702/ /pubmed/24700960 http://dx.doi.org/10.4103/0019-5154.127715 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle E-Case Report
Shingade, Pravin U
Wankhede, Vaishali
Kataria, Pritam S
Sonone, Nitin
Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title_full Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title_fullStr Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title_full_unstemmed Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title_short Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
title_sort rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome
topic E-Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969702/
https://www.ncbi.nlm.nih.gov/pubmed/24700960
http://dx.doi.org/10.4103/0019-5154.127715
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AT katariapritams rarecaseofphenytoininducedacutegeneralizedexanthematouspustulosiswithcerebellarsyndrome
AT sononenitin rarecaseofphenytoininducedacutegeneralizedexanthematouspustulosiswithcerebellarsyndrome

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