Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease. To elucidate the molecular basis of NAFLD we performed an exome-wide association study of liver fat content. Three variants were associated with increased liver fat at the exome-wide significance level: two in PNPLA3,...

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Detalles Bibliográficos
Autores principales: Kozlitina, Julia, Smagris, Eriks, Stender, Stefan, Nordestgaard, Børge G., Zhou, Heather H., Tybjærg-Hansen, Anne, Vogt, Thomas F., Hobbs, Helen H., Cohen, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969786/
https://www.ncbi.nlm.nih.gov/pubmed/24531328
http://dx.doi.org/10.1038/ng.2901

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