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Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy

Duchenne's muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as...

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Autores principales: Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad, Sanfilippo, Maria, Sabba, Antonio, Pinchera, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970074/
https://www.ncbi.nlm.nih.gov/pubmed/24715988
http://dx.doi.org/10.1155/2014/680568
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author Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Sanfilippo, Maria
Sabba, Antonio
Pinchera, Paolo
author_facet Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Sanfilippo, Maria
Sabba, Antonio
Pinchera, Paolo
author_sort Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
collection PubMed
description Duchenne's muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as prolonged recovery from anesthesia. In this case report, we describe a 25-year-old male patient admitted for cholecystectomy under general anesthesia. We induced our anesthesia by oxygen, propofol, fentanyl, and rocuronium bromide. Maintenance was done by fentanyl, rocuronium bromide, sevoflurane, and O(2). We report in this case the safety use of sugammadex to antagonize the neuromuscular block and rapid recovery in such category of patients.
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spelling pubmed-39700742014-04-08 Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad Sanfilippo, Maria Sabba, Antonio Pinchera, Paolo Case Rep Anesthesiol Case Report Duchenne's muscular dystrophy (DMD) is the most common and severe form of myopathy. Patients with DMD are more sensitive to sedative, anesthetic, and neuromuscular blocking agents which may result in intraoperative and early postoperative cardiovascular and respiratory complications, as well as prolonged recovery from anesthesia. In this case report, we describe a 25-year-old male patient admitted for cholecystectomy under general anesthesia. We induced our anesthesia by oxygen, propofol, fentanyl, and rocuronium bromide. Maintenance was done by fentanyl, rocuronium bromide, sevoflurane, and O(2). We report in this case the safety use of sugammadex to antagonize the neuromuscular block and rapid recovery in such category of patients. Hindawi Publishing Corporation 2014 2014-03-13 /pmc/articles/PMC3970074/ /pubmed/24715988 http://dx.doi.org/10.1155/2014/680568 Text en Copyright © 2014 Ahmed Abdelgawwad Wefki Abdelgawwad Shousha et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Wefki Abdelgawwad Shousha, Ahmed Abdelgawwad
Sanfilippo, Maria
Sabba, Antonio
Pinchera, Paolo
Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_full Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_fullStr Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_full_unstemmed Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_short Sugammadex and Reversal of Neuromuscular Block in Adult Patient with Duchenne Muscular Dystrophy
title_sort sugammadex and reversal of neuromuscular block in adult patient with duchenne muscular dystrophy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970074/
https://www.ncbi.nlm.nih.gov/pubmed/24715988
http://dx.doi.org/10.1155/2014/680568
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