Predictive combinatorial design of mRNA translation initiation regions for systematic optimization of gene expression levels

Balancing the amounts of enzymes is one of the important factors to achieve optimum performance of a designed metabolic pathway. However, the random mutagenesis approach is impractical since it requires searching an unnecessarily large number of variants and often results in searching a narrow range...

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Detalles Bibliográficos
Autores principales: Seo, Sang Woo, Yang, Jae-Seong, Cho, Han-Saem, Yang, Jina, Kim, Seong Cheol, Park, Jong Moon, Kim, Sanguk, Jung, Gyoo Yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970122/
https://www.ncbi.nlm.nih.gov/pubmed/24682040
http://dx.doi.org/10.1038/srep04515

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