Cargando…
A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction
Knowledge of genes essential for the life-extending effect of dietary restriction (DR) in mammals is incomplete. In this study, we found that neuropeptide Y (Npy), which mediates physiological adaptations to energy deficits, is an essential link between DR and longevity in mice. The lifespan-prolong...
Autores principales: | Chiba, Takuya, Tamashiro, Yukari, Park, Daeui, Kusudo, Tatsuya, Fujie, Ryoko, Komatsu, Toshimitsu, Kim, Sang Eun, Park, Seongjoon, Hayashi, Hiroko, Mori, Ryoichi, Yamashita, Hitoshi, Chung, Hae Young, Shimokawa, Isao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970128/ https://www.ncbi.nlm.nih.gov/pubmed/24682105 http://dx.doi.org/10.1038/srep04517 |
Ejemplares similares
-
The Role of Neuropeptide Y in Adipocyte-Macrophage Crosstalk during High Fat Diet-Induced Adipose Inflammation and Liver Steatosis
por: Park, Seongjoon, et al.
Publicado: (2021) -
Neuropeptide Y resists excess loss of fat by lipolysis in calorie‐restricted mice: a trait potential for the life‐extending effect of calorie restriction
por: Park, Seongjoon, et al.
Publicado: (2017) -
The fat regulator neuropeptide Y and caloric restriction
por: Park, Seongjoon, et al.
Publicado: (2017) -
Mechanisms of Calorie Restriction: A Review of Genes Required for the Life-Extending and Tumor-Inhibiting Effects of Calorie Restriction
por: Komatsu, Toshimitsu, et al.
Publicado: (2019) -
The life-extending effect of dietary restriction requires Foxo3 in mice
por: Shimokawa, Isao, et al.
Publicado: (2015)