Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer

Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium...

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Detalles Bibliográficos
Autores principales: Choi, Ji Hoon, Shin, Jung A., Park, Hye Kyeong, Kim, Su Young, Jung, Hoon, Lee, Sung-Soon, Lee, Hye Ran, Koo, Hyeon-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970254/
https://www.ncbi.nlm.nih.gov/pubmed/24716039
http://dx.doi.org/10.1155/2014/203027
Descripción
Sumario:Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium folinic acid, and oxaliplatin: FOLFOX). Nodular consolidation progressed despite antibiotics and BAL fluid analysis was compatible with the diagnosis of sarcoidosis. Corticosteroid therapy rapidly improved the symptoms and radiographic findings. We report this first case of secondary sarcoidosis related to FOLFOX therapy with review of references.

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