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Underestimation of the Calculated Area Under the Concentration-Time Curve Based on Serum Creatinine for Vancomycin Dosing

BACKGROUND: The ratio of the steady-state 24-hour area under the concentration-time curve (ssAUC(24)) to the MIC (AUC(24)/MIC) for vancomycin has been recommended as the preferred pharmacodynamic index. The aim of this study was to assess whether the calculated AUC(24) (cAUC(24)) using the creatinin...

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Detalles Bibliográficos
Autores principales: Jin, Sung Joon, Yoon, Ji Hyun, Ahn, Bo Sook, Chung, Ji Ah, Song, Young Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970305/
https://www.ncbi.nlm.nih.gov/pubmed/24693466
http://dx.doi.org/10.3947/ic.2014.46.1.21