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Severe Acute Radiation Dermatitis in a Patient with Argyria
Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970361/ https://www.ncbi.nlm.nih.gov/pubmed/24716038 http://dx.doi.org/10.1155/2014/154349 |
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author | Gorayski, P. Pinkham, M. B. Muir, J. B. Pullar, A. P. |
author_facet | Gorayski, P. Pinkham, M. B. Muir, J. B. Pullar, A. P. |
author_sort | Gorayski, P. |
collection | PubMed |
description | Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered. |
format | Online Article Text |
id | pubmed-3970361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-39703612014-04-08 Severe Acute Radiation Dermatitis in a Patient with Argyria Gorayski, P. Pinkham, M. B. Muir, J. B. Pullar, A. P. Case Rep Oncol Med Case Report Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered. Hindawi Publishing Corporation 2014 2014-03-03 /pmc/articles/PMC3970361/ /pubmed/24716038 http://dx.doi.org/10.1155/2014/154349 Text en Copyright © 2014 P. Gorayski et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Gorayski, P. Pinkham, M. B. Muir, J. B. Pullar, A. P. Severe Acute Radiation Dermatitis in a Patient with Argyria |
title | Severe Acute Radiation Dermatitis in a Patient with Argyria |
title_full | Severe Acute Radiation Dermatitis in a Patient with Argyria |
title_fullStr | Severe Acute Radiation Dermatitis in a Patient with Argyria |
title_full_unstemmed | Severe Acute Radiation Dermatitis in a Patient with Argyria |
title_short | Severe Acute Radiation Dermatitis in a Patient with Argyria |
title_sort | severe acute radiation dermatitis in a patient with argyria |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970361/ https://www.ncbi.nlm.nih.gov/pubmed/24716038 http://dx.doi.org/10.1155/2014/154349 |
work_keys_str_mv | AT gorayskip severeacuteradiationdermatitisinapatientwithargyria AT pinkhammb severeacuteradiationdermatitisinapatientwithargyria AT muirjb severeacuteradiationdermatitisinapatientwithargyria AT pullarap severeacuteradiationdermatitisinapatientwithargyria |