Cargando…

Dense genomic sampling identifies highways of pneumococcal recombination

Evasion of clinical interventions by Streptococcus pneumoniae occurs through selection of non-susceptible genomic variants. Here we use genome sequencing of 3,085 pneumococcal carriage isolates from a 2.4 km(2) refugee camp to enable unprecedented resolution of the process of recombination, and high...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chewapreecha, Claire, Harris, Simon R, Croucher, Nicholas J, Turner, Claudia, Marttinen, Pekka, Cheng, Lu, Pessia, Alberto, Aanensen, David M, Mather, Alison E, Page, Andrew J, Salter, Susannah J., Harris, David, Nosten, Francois, Goldblatt, David, Corander, Jukka, Parkhill, Julian, Turner, Paul, Bentley, Stephen D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970364/ https://www.ncbi.nlm.nih.gov/pubmed/24509479 http://dx.doi.org/10.1038/ng.2895

Ejemplares similares

Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes
por: Chewapreecha, Claire, et al.
Publicado: (2014)

Climate induces seasonality in pneumococcal transmission
por: Numminen, Elina, et al.
Publicado: (2015)

Corrigendum: Climate induces seasonality in pneumococcal transmission
por: Numminen, Elina, et al.
Publicado: (2016)

Pneumococcal Capsule Synthesis Locus cps as Evolutionary Hotspot with Potential to Generate Novel Serotypes by Recombination
por: Mostowy, Rafał J., et al.
Publicado: (2017)

Genome-wide identification of lineage and locus specific variation associated with pneumococcal carriage duration
por: Lees, John A, et al.
Publicado: (2017)

Pneumococcal within-host diversity during colonization, transmission and treatment
por: Tonkin-Hill, Gerry, et al.
Publicado: (2022)

Detection of recombination events in bacterial genomes from large population samples
por: Marttinen, Pekka, et al.
Publicado: (2012)

Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes
por: Lees, John A., et al.
Publicado: (2016)

A longitudinal study of the infant nasopharyngeal microbiota: The effects of age, illness and antibiotic use in a cohort of South East Asian children
por: Salter, Susannah J., et al.
Publicado: (2017)

Two-phase importance sampling for inference about transmission trees
por: Numminen, Elina, et al.
Publicado: (2014)

A High-Resolution View of Genome-Wide Pneumococcal Transformation
por: Croucher, Nicholas J., et al.
Publicado: (2012)

A prospective study of urinary pneumococcal antigen detection in healthy Karen mothers with high rates of pneumococcal nasopharyngeal carriage
por: Turner, Paul, et al.
Publicado: (2011)

Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
por: Skwark, Marcin J., et al.
Publicado: (2017)

Recombination produces coherent bacterial species clusters in both core and accessory genomes
por: Marttinen, Pekka, et al.
Publicado: (2015)

Evidence for Soft Selective Sweeps in the Evolution of Pneumococcal Multidrug Resistance and Vaccine Escape
por: Croucher, Nicholas J., et al.
Publicado: (2014)

Efficient Bayesian approach for multilocus association mapping including gene-gene interactions
por: Marttinen, Pekka, et al.
Publicado: (2010)

PANINI: Pangenome Neighbour Identification for Bacterial Populations
por: Abudahab, Khalil, et al.
Publicado: (2018)

Identification, variation and transcription of pneumococcal repeat sequences
por: Croucher, Nicholas J, et al.
Publicado: (2011)

Efficient Inference of Recent and Ancestral Recombination within Bacterial Populations
por: Mostowy, Rafal, et al.
Publicado: (2017)

Field Evaluation of Culture plus Latex Sweep Serotyping for Detection of Multiple Pneumococcal Serotype Colonisation in Infants and Young Children
por: Turner, Paul, et al.
Publicado: (2013)

Frequency-dependent selection in vaccine-associated pneumococcal population dynamics
por: Corander, Jukka, et al.
Publicado: (2017)

Bayesian clustering and feature selection for cancer tissue samples
por: Marttinen, Pekka, et al.
Publicado: (2009)

Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations
por: Corander, Jukka, et al.
Publicado: (2008)

Diversification of Colonization Factors in a Multidrug-Resistant Escherichia coli Lineage Evolving under Negative Frequency-Dependent Selection
por: McNally, Alan, et al.
Publicado: (2019)

Pneumococcal Infection among Children before Introduction of 13-Valent Pneumococcal Conjugate Vaccine, Cambodia
por: Turner, Paul, et al.
Publicado: (2015)

Heterogeneity in the Frequency and Characteristics of Homologous Recombination in Pneumococcal Evolution
por: Mostowy, Rafal, et al.
Publicado: (2014)

Genome-wide epistasis and co-selection study using mutual information
por: Pensar, Johan, et al.
Publicado: (2019)

Kpax3: Bayesian bi-clustering of large sequence datasets
por: Pessia, Alberto, et al.
Publicado: (2018)

Genome-wide association, prediction and heritability in bacteria with application to Streptococcus pneumoniae
por: Mallawaarachchi, Sudaraka, et al.
Publicado: (2022)

Selective and Genetic Constraints on Pneumococcal Serotype Switching
por: Croucher, Nicholas J., et al.
Publicado: (2015)

Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus
por: Castillo-Ramírez, Santiago, et al.
Publicado: (2012)

Genetic Analysis of the Capsular Biosynthetic Locus from All 90 Pneumococcal Serotypes
por: Bentley, Stephen D, et al.
Publicado: (2006)

International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact
por: Gladstone, Rebecca A., et al.
Publicado: (2019)

Serum antibody responses to pneumococcal colonization in the first 2 years of life: results from an SE Asian longitudinal cohort study
por: Turner, P, et al.
Publicado: (2013)

Pneumococcal pneumonia
por: Goldblatt, David, et al.
Publicado: (2020)

Population genomics of post-vaccine changes in pneumococcal epidemiology
por: Croucher, Nicholas J., et al.
Publicado: (2013)

Hierarchical and Spatially Explicit Clustering of DNA Sequences with BAPS Software
por: Cheng, Lu, et al.
Publicado: (2013)

Bayesian modeling of recombination events in bacterial populations
por: Marttinen, Pekka, et al.
Publicado: (2008)

Genetic Characterisation of Malawian Pneumococci Prior to the Roll-Out of the PCV13 Vaccine Using a High-Throughput Whole Genome Sequencing Approach
por: Everett, Dean B., et al.
Publicado: (2012)

Understanding pneumococcal serotype 1 biology through population genomic analysis
por: Chaguza, Chrispin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_l1v2nba8rsl53em64lddnub20g