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Fatal Acute Right Heart Failure in Gastric Cancer Patients
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiogr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970374/ https://www.ncbi.nlm.nih.gov/pubmed/24696760 http://dx.doi.org/10.4103/1995-705X.126883 |
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author | Seol, Sang-Hoon Park, Bo-Min Jin, Han-Young Kim, Doo-Il |
author_facet | Seol, Sang-Hoon Park, Bo-Min Jin, Han-Young Kim, Doo-Il |
author_sort | Seol, Sang-Hoon |
collection | PubMed |
description | Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiography reveals a dilated right ventricle and feature of pulmonary artery hypertension. Establishing this diagnosis can be very difficult, and most cases are diagnosed during autopsy, although a history of cancer may be a predictor. PTTM should be considered in all patients with apparent pulmonary artery hypertension and elevated D-dimer level, particularly when the patient is known to have an underlying malignancy, especially adenocarcinoma and most of all, the clinical manifestation is very rapidly progressive. |
format | Online Article Text |
id | pubmed-3970374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39703742014-04-02 Fatal Acute Right Heart Failure in Gastric Cancer Patients Seol, Sang-Hoon Park, Bo-Min Jin, Han-Young Kim, Doo-Il Heart Views Case Report Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiography reveals a dilated right ventricle and feature of pulmonary artery hypertension. Establishing this diagnosis can be very difficult, and most cases are diagnosed during autopsy, although a history of cancer may be a predictor. PTTM should be considered in all patients with apparent pulmonary artery hypertension and elevated D-dimer level, particularly when the patient is known to have an underlying malignancy, especially adenocarcinoma and most of all, the clinical manifestation is very rapidly progressive. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3970374/ /pubmed/24696760 http://dx.doi.org/10.4103/1995-705X.126883 Text en Copyright: © Heart Views http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Seol, Sang-Hoon Park, Bo-Min Jin, Han-Young Kim, Doo-Il Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title | Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title_full | Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title_fullStr | Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title_full_unstemmed | Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title_short | Fatal Acute Right Heart Failure in Gastric Cancer Patients |
title_sort | fatal acute right heart failure in gastric cancer patients |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970374/ https://www.ncbi.nlm.nih.gov/pubmed/24696760 http://dx.doi.org/10.4103/1995-705X.126883 |
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