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Fatal Acute Right Heart Failure in Gastric Cancer Patients

Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiogr...

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Autores principales: Seol, Sang-Hoon, Park, Bo-Min, Jin, Han-Young, Kim, Doo-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970374/
https://www.ncbi.nlm.nih.gov/pubmed/24696760
http://dx.doi.org/10.4103/1995-705X.126883
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author Seol, Sang-Hoon
Park, Bo-Min
Jin, Han-Young
Kim, Doo-Il
author_facet Seol, Sang-Hoon
Park, Bo-Min
Jin, Han-Young
Kim, Doo-Il
author_sort Seol, Sang-Hoon
collection PubMed
description Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiography reveals a dilated right ventricle and feature of pulmonary artery hypertension. Establishing this diagnosis can be very difficult, and most cases are diagnosed during autopsy, although a history of cancer may be a predictor. PTTM should be considered in all patients with apparent pulmonary artery hypertension and elevated D-dimer level, particularly when the patient is known to have an underlying malignancy, especially adenocarcinoma and most of all, the clinical manifestation is very rapidly progressive.
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spelling pubmed-39703742014-04-02 Fatal Acute Right Heart Failure in Gastric Cancer Patients Seol, Sang-Hoon Park, Bo-Min Jin, Han-Young Kim, Doo-Il Heart Views Case Report Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare condition causing pulmonary artery hypertension and acute right heart failure in patients with cancer. However, chest computer tomography shows negative finding of pulmonary thromboembolism. Serum D-dimer level may be elevated. Echocardiography reveals a dilated right ventricle and feature of pulmonary artery hypertension. Establishing this diagnosis can be very difficult, and most cases are diagnosed during autopsy, although a history of cancer may be a predictor. PTTM should be considered in all patients with apparent pulmonary artery hypertension and elevated D-dimer level, particularly when the patient is known to have an underlying malignancy, especially adenocarcinoma and most of all, the clinical manifestation is very rapidly progressive. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3970374/ /pubmed/24696760 http://dx.doi.org/10.4103/1995-705X.126883 Text en Copyright: © Heart Views http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Seol, Sang-Hoon
Park, Bo-Min
Jin, Han-Young
Kim, Doo-Il
Fatal Acute Right Heart Failure in Gastric Cancer Patients
title Fatal Acute Right Heart Failure in Gastric Cancer Patients
title_full Fatal Acute Right Heart Failure in Gastric Cancer Patients
title_fullStr Fatal Acute Right Heart Failure in Gastric Cancer Patients
title_full_unstemmed Fatal Acute Right Heart Failure in Gastric Cancer Patients
title_short Fatal Acute Right Heart Failure in Gastric Cancer Patients
title_sort fatal acute right heart failure in gastric cancer patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970374/
https://www.ncbi.nlm.nih.gov/pubmed/24696760
http://dx.doi.org/10.4103/1995-705X.126883
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