Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis

Objective. The aim of this study was to identify serum markers that are modulated by an investigational anti-IFN-α mAb, sifalimumab, in adult DM or PM patients. Methods. In a phase 1b clinical trial, sera were collected from a total of 48 DM or PM adult patients receiving either placebo for 3 months...

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Detalles Bibliográficos
Autores principales: Guo, Xiang, Higgs, Brandon W., Rebelatto, Marlon, Zhu, Wei, Greth, Warren, Yao, Yihong, Roskos, Lorin K., White, Wendy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Clinical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970566/
https://www.ncbi.nlm.nih.gov/pubmed/24357810
http://dx.doi.org/10.1093/rheumatology/ket413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970566/
https://www.ncbi.nlm.nih.gov/pubmed/24357810
http://dx.doi.org/10.1093/rheumatology/ket413

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