Cargando…
Suppression of soluble T cell-associated proteins by an anti-interferon-α monoclonal antibody in adult patients with dermatomyositis or polymyositis
Objective. The aim of this study was to identify serum markers that are modulated by an investigational anti-IFN-α mAb, sifalimumab, in adult DM or PM patients. Methods. In a phase 1b clinical trial, sera were collected from a total of 48 DM or PM adult patients receiving either placebo for 3 months...
Autores principales: | Guo, Xiang, Higgs, Brandon W., Rebelatto, Marlon, Zhu, Wei, Greth, Warren, Yao, Yihong, Roskos, Lorin K., White, Wendy I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970566/ https://www.ncbi.nlm.nih.gov/pubmed/24357810 http://dx.doi.org/10.1093/rheumatology/ket413 |
Ejemplares similares
-
A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients
por: Higgs, Brandon W, et al.
Publicado: (2014) -
Nutrition and Polymyositis and Dermatomyositis
por: Loell, Ingela, et al.
Publicado: (2008) -
Population Pharmacokinetics of Sifalimumab, an Investigational Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus
por: Narwal, Rajesh, et al.
Publicado: (2013) -
Viral Etiology of Polymyositis/Dermatomyositis
por: DENMAN, A.M.
Publicado: (1988) -
Subcutaneous Edema in Polymyositis and Dermatomyositis
por: Yoshimi, Ryusuke, et al.
Publicado: (2023)