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Infection in a rat model reactivates attenuated virulence after long-term axenic culture of Acanthamoeba spp
Prolonged culturing of many microorganisms leads to the loss of virulence and a reduction of their infective capacity. However, little is known about the changes in the pathogenic strains of Acanthamoeba after long culture periods. Our study evaluated the effect of prolonged culturing on the invasiv...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970641/ https://www.ncbi.nlm.nih.gov/pubmed/24271042 http://dx.doi.org/10.1590/0074-0276130099 |