Serologic survey of West Nile virus in horses from Central-West, Northeast and Southeast Brazil

Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain...

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Detalles Bibliográficos
Autores principales: Silva, Jaqueline Raymondi, de Medeiros, Larissa Campos, dos Reis, Vinícius Pinho, Chávez, Juliana Helena, Munhoz, Thiago Demarchi, Borges, Gustavo Puia, Soares, Otavio Augusto Brioschi, de Campos, Carlos Henrique Coelho, Machado, Rosângela Zacarias, Baldani, Cristiane Divan, Silva, Maria Luana Cristiny Rodrigues, Faria, Joice Lara Maia, da Silva, Edson Elias, Figueiredo, Luiz Tadeu Moraes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz 2013
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970643/
https://www.ncbi.nlm.nih.gov/pubmed/24037110
http://dx.doi.org/10.1590/0074-0276130052
Descripción
Sumario:Since the emergence of West Nile virus (WNV) in North America in 1999, there have been several reports of WNV activity in Central and South American countries. To detect WNV in Brazil, we performed a serological survey of horses from different regions of Brazil using recombinant peptides from domain III of WNV. Positive samples were validated with the neutralisation test. Our results showed that of 79 ELISA-positive horses, nine expressed WNV-specific neutralising antibodies. Eight of the infected horses were from the state of Mato Grosso do Sul and one was from the state of Paraíba. Our results provide additional evidence for the emergence of WNV in Brazil and for its circulation in multiple regions of the country.

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