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Sphingosine‐1‐phosphate acts as a key molecule in the direct mediation of renal fibrosis

The major sphingolipid metabolite, sphingosine‐1‐phosphate (S1P), has important biological functions. S1P serves as a ligand for a family of five G‐protein‐coupled receptors with distinct signaling pathways regulating important biological pathways. S1P induces renal fibrosis through an inflammatory...

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Detalles Bibliográficos
Autores principales:	Shiohira, Shunji, Yoshida, Takumi, Sugiura, Hidekazu, Nishida, Miki, Nitta, Kosaku, Tsuchiya, Ken
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Periodicals, Inc. 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970738/ https://www.ncbi.nlm.nih.gov/pubmed/24744854 http://dx.doi.org/10.1002/phy2.172

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