Differential effects of Smad3 targeting in a murine model of chronic kidney disease

Transforming growth factor (TGF)‐β1 has a pivotal role in the pathogenesis of progressive kidney diseases that are characterized by fibrosis. The main intracellular signaling pathway of TGF‐β1 is the Smad system, where Smad2 and Smad3 play a central role in transcriptional regulation of target genes...

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Detalles Bibliográficos
Autores principales: Kellenberger, Terese, Krag, Søren, Danielsen, Carl Christian, Wang, Xiao‐Fan, Nyengaard, Jens Randel, Pedersen, Lea, Yang, Chuanxu, Gao, Shan, Wogensen, Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970747/
https://www.ncbi.nlm.nih.gov/pubmed/24744860
http://dx.doi.org/10.1002/phy2.181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970747/
https://www.ncbi.nlm.nih.gov/pubmed/24744860
http://dx.doi.org/10.1002/phy2.181

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