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Effect of (2)H and (18)O water isotopes in kinesin-1 gliding assay

We show for the first time the effects of heavy-hydrogen water ((2)H(2)O) and heavy-oxygen water (H(2)(18)O) on the gliding speed of microtubules on kinesin-1 coated surfaces. Increased fractions of isotopic waters used in the motility solution decreased the gliding speed of microtubules by a maximu...

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Detalles Bibliográficos
Autores principales:	Maloney, Andy, Herskowitz, Lawrence J., Koch, Steven J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2014
Materias:	Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970804/ https://www.ncbi.nlm.nih.gov/pubmed/24711961 http://dx.doi.org/10.7717/peerj.284

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