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Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line

Breast cancer is the most frequent cancer affecting women. Methotrexate (MTX) is an antimetabolic drug that remains important in the treatment of breast cancer. Its efficacy is compromised by resistance in cancer cells that occurs through a variety of mechanisms. This study evaluated apoptotic cell...

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Detalles Bibliográficos
Autores principales:	Yurgel, Virginia C, Oliveira, Catiuscia P, Begnini, Karine R, Schultze, Eduarda, Thurow, Helena S, Leon, Priscila MM, Dellagostin, Odir A, Campos, Vinicius F, Beck, Ruy CR, Guterres, Silvia S, Collares, Tiago, Pohlmann, Adriana R, Seixas, Fabiana K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970944/ https://www.ncbi.nlm.nih.gov/pubmed/24741306 http://dx.doi.org/10.2147/IJN.S56506

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