Cargando…
Convergence of Hypoxia and TGFβ Pathways on Cell Cycle Regulation in Human Hematopoietic Stem/Progenitor Cells
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are involved. We identified transcriptome changes induced by hypoxia, constitutively active HIF1((P402/56...
Autores principales: | Wierenga, Albertus T. J., Vellenga, Edo, Schuringa, Jan Jacob |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970968/ https://www.ncbi.nlm.nih.gov/pubmed/24686421 http://dx.doi.org/10.1371/journal.pone.0093494 |
Ejemplares similares
-
STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells
por: Schepers, Hein, et al.
Publicado: (2012) -
Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses
por: Han, Lina, et al.
Publicado: (2009) -
ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML
por: Capala, Marta E., et al.
Publicado: (2014) -
HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells
por: Wierenga, Albertus T. J., et al.
Publicado: (2019) -
Hypoxia-Like Signatures Induced by BCR-ABL Potentially Alter the Glutamine Uptake for Maintaining Oxidative Phosphorylation
por: Sontakke, Pallavi, et al.
Publicado: (2016)