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CYP2C8 and CYP2C9 mRNA expression profile in the human fetus

CYP2C8 and CYP2C9 are involved in the inactivation of several non-steroidal anti-inflammatory drugs, including ibuprofen. CYP2C9 is the major form in human liver whereas CYP2C8 has been proposed to be the main CYP2C enzyme in fetal liver. The protein expression of CYP2C9 in the first trimester is lo...

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Detalles Bibliográficos
Autores principales:	Johansson, Maria, Strahm, Emmanuel, Rane, Anders, Ekström, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971157/ https://www.ncbi.nlm.nih.gov/pubmed/24723938 http://dx.doi.org/10.3389/fgene.2014.00058

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