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Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy
The type II AAA+ protein p97 is involved in numerous cellular activities, including endoplasmic reticulum-associated degradation, transcription activation, membrane fusion and cell-cycle control. These activities are at least in part regulated by the ubiquitin system, in which p97 is thought to targ...
Autores principales: | Yeung, Heidi O., Förster, Andreas, Bebeacua, Cecilia, Niwa, Hajime, Ewens, Caroline, McKeown, Ciarán, Zhang, Xiaodong, Freemont, Paul S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971404/ https://www.ncbi.nlm.nih.gov/pubmed/24598262 http://dx.doi.org/10.1098/rsob.130142 |
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