The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity

The G-protein-coupled receptor (GPCR) signaling system is one of the main signaling pathways in eukaryotes. Here, we analyze the evolutionary history of all its components, from receptors to regulators, to gain a broad picture of its system-level evolution. Using eukaryotic genomes covering most lin...

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Detalles Bibliográficos
Autores principales: de Mendoza, Alex, Sebé-Pedrós, Arnau, Ruiz-Trillo, Iñaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971589/
https://www.ncbi.nlm.nih.gov/pubmed/24567306
http://dx.doi.org/10.1093/gbe/evu038

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