Cargando…

Synthesis of Pandamarilactone-1

[Image: see text] The first total synthesis of pandamarilactone-1, an alkaloid of Pandanus amaryllifolius, is reported. The nine-step synthesis features furan oxidation with singlet oxygen and then spiro-N,O-acetalization and elimination to generate the natural product and further Pandanus alkaloids...

Descripción completa

Detalles Bibliográficos
Autores principales: Seah, Kang Yee, Macnaughton, Sarah J., Dallimore, Jonathan W. P., Robertson, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971736/
https://www.ncbi.nlm.nih.gov/pubmed/24479880
http://dx.doi.org/10.1021/ol4036424
_version_ 1782309512447787008
author Seah, Kang Yee
Macnaughton, Sarah J.
Dallimore, Jonathan W. P.
Robertson, Jeremy
author_facet Seah, Kang Yee
Macnaughton, Sarah J.
Dallimore, Jonathan W. P.
Robertson, Jeremy
author_sort Seah, Kang Yee
collection PubMed
description [Image: see text] The first total synthesis of pandamarilactone-1, an alkaloid of Pandanus amaryllifolius, is reported. The nine-step synthesis features furan oxidation with singlet oxygen and then spiro-N,O-acetalization and elimination to generate the natural product and further Pandanus alkaloids, pandamarilactonines A–D.
format Online
Article
Text
id pubmed-3971736
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-39717362014-04-01 Synthesis of Pandamarilactone-1 Seah, Kang Yee Macnaughton, Sarah J. Dallimore, Jonathan W. P. Robertson, Jeremy Org Lett [Image: see text] The first total synthesis of pandamarilactone-1, an alkaloid of Pandanus amaryllifolius, is reported. The nine-step synthesis features furan oxidation with singlet oxygen and then spiro-N,O-acetalization and elimination to generate the natural product and further Pandanus alkaloids, pandamarilactonines A–D. American Chemical Society 2014-01-30 2014-02-07 /pmc/articles/PMC3971736/ /pubmed/24479880 http://dx.doi.org/10.1021/ol4036424 Text en Copyright © 2014 American Chemical Society Terms of Use CC-BY (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html)
spellingShingle Seah, Kang Yee
Macnaughton, Sarah J.
Dallimore, Jonathan W. P.
Robertson, Jeremy
Synthesis of Pandamarilactone-1
title Synthesis of Pandamarilactone-1
title_full Synthesis of Pandamarilactone-1
title_fullStr Synthesis of Pandamarilactone-1
title_full_unstemmed Synthesis of Pandamarilactone-1
title_short Synthesis of Pandamarilactone-1
title_sort synthesis of pandamarilactone-1
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971736/
https://www.ncbi.nlm.nih.gov/pubmed/24479880
http://dx.doi.org/10.1021/ol4036424
work_keys_str_mv AT seahkangyee synthesisofpandamarilactone1
AT macnaughtonsarahj synthesisofpandamarilactone1
AT dallimorejonathanwp synthesisofpandamarilactone1
AT robertsonjeremy synthesisofpandamarilactone1