Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system

The PI 3-kinase (PI 3-K) signaling pathway is essential for Schwann cell myelination. Here we have characterized PI 3-K effectors activated during myelination by probing myelinating cultures and developing nerves with an antibody that recognizes phosphorylated substrates for this pathway. We identif...

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Detalles Bibliográficos
Autores principales: Heller, Bradley A., Ghidinelli, Monica, Voelkl, Jakob, Einheber, Steven, Smith, Ryan, Grund, Ethan, Morahan, Grant, Chandler, David, Kalaydjieva, Luba, Giancotti, Filippo, King, Rosalind H., Fejes-Toth, Aniko Naray, Fejes-Toth, Gerard, Feltri, Maria Laura, Lang, Florian, Salzer, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971744/
https://www.ncbi.nlm.nih.gov/pubmed/24687281
http://dx.doi.org/10.1083/jcb.201307057

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